منابع مشابه
Genotoxicity Assessment of Multispecies Probiotics Using Reverse Mutation, Mammalian Chromosomal Aberration, and Rodent Micronucleus Tests
Genotoxicity assessment is carried out on freeze dried powder of cultured probiotics containing Lactobacillus rhamnosus LCR177, Bifidobacterium adolescentis BA286, and Pediococcus acidilactici PA318. Ames tests, in vitro mammalian chromosome aberration assay, and micronucleus tests in mouse peripheral blood are performed. For 5 strains of Salmonella Typhimurium, the Ames tests show no increased...
متن کاملIn vivo determination of genotoxicity induced by metals from orthodontic appliances using micronucleus and comet assays.
Orthodontic appliances are usually made of stainless steel, which contains metals such as nickel, chromium and iron that have been associated with DNA damage. The aim of the present study was to determine the genetic toxicity associated with orthodontic fixed appliances in twenty healthy patients (16 +/- 2.5 years) undergoing orthodontic treatment (fixed appliances - basic composition: stainles...
متن کاملGenotoxicity Assessment of Acrylamide in Early Developing Stages of Chick Embryo Using Micronucleus Assay
The micronucleus (MN) test in bone-marrow and peripheral blood erythrocytes is one of the best established in vivo cytogenetic assays in the field of genetic toxicology, providing a convenient and reliable index of both chromosome breakage and chromosome loss. Therefore a study was made on micronuclei assay to evaluate the degree of genotoxicity of acrylamide and its toxicologic effects on chic...
متن کاملOccupational genotoxicity risk evaluation through the comet assay and the micronucleus test.
The micronucleus (MN) test and the alkaline single cell gel or comet assay were applied to exfoliated cells of the buccal mucous in order to evaluate the genotoxic risk associated with occupational exposure of 10 storage battery renovation workers, and 10 car painters, with age matched controls, in Pelotas, RS, in southern Brazil. In the MN test, 2000 exfoliated buccal cells were analyzed for e...
متن کاملUse of nasal cells in micronucleus assays and other genotoxicity studies.
Genotoxicity experiments with exfoliated nasal mucosa cells are a promising minimally invasive approach for the detection of DNA-damaging compounds in ambient air. Results of single cell gel electrophoresis (SCGE) assays with individual cells and organ cultures from bioptic material show that DNA damage caused by compounds such as nitrosamines, polycyclic aromatic hydrocarbons and pesticides ca...
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ژورنال
عنوان ژورنال: Turkiye Klinikleri Journal of Medical Sciences
سال: 2019
ISSN: 1300-0292,2146-9040
DOI: 10.5336/medsci.2018-62147